XGEVA FIRST STEP Program Card Registration
Welcome to the XGEVA FIRST STEP Program. Please complete the online form below to register your card.
If you have any questions or problems using your card after registration, please call 1-888-65-STEP1 (1-888-657-8371) from 9 a.m. to 8 p.m. ET, Monday-Friday except holidays.

Please verify that all the information is correct and press submit when complete.
Indication
XGEVA® is a prescription medicine used to prevent bone problems in patients with bone metastases from solid tumors.
XGEVA® is not used to prevent bone problems in patients with multiple myeloma..
What is the most important information I should know about XGEVA®?
Low calcium levels in your blood (hypocalcemia)
XGEVA® can significantly lower the calcium levels in your blood. Your low blood calcium must be treated before you receive XGEVA®. Your doctor may prescribe calcium and vitamin D to help prevent low calcium levels in your blood while you take XGEVA®. Take calcium and vitamin D as your doctor tells you to.
Severe jaw bone problems (osteonecrosis)
Severe jaw bone problems may happen when you take XGEVA®. Your doctor should examine your mouth before you start, and while you are taking XGEVA®. Tell your dentist that you are taking XGEVA®. It is important for you to practice good mouth care during treatment with XGEVA®
Before taking XGEVA®, tell your doctor if you:
- Have low blood calcium
- Cannot take daily calcium and vitamin D
- Have kidney problems or are on kidney dialysis
- Plan to have dental surgery or teeth removed
- Are pregnant or plan to become pregnant
- Are breast-feeding or plan to breast-feed
What are the possible side effects of XGEVA®?
The most common side effects of XGEVA® are tiredness/weakness, low phosphate levels in your blood, and nausea. The most common serious side effect of XGEVA® is shortness of breath.
These are not all the possible side effects of XGEVA® . For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see Prescribing Information for more information about XGEVA®.
